Hi, the answer to your question is a yes. Both the Yeoman plotter and Megellan 320 are NMEA-0183 compliant. NMEA-0183 is the data link used in the marine industry to allow different manufactures products to be interface. When you by the Yeomen it will tell you exaclty which wires need to go where, as should the manual for your GPS. My father bought a Yeomen several years ago and linked it to an old Megellan GPS with no trouble. A great peace of kit which is very useful.